
Prof. Junfang Zheng
, China
Biography:
1. Dai CY#, Tang YG#, Yang HH, Zheng JF*. YTHDC1 lactylation regulates its phase separation to enhance target mRNA stability and promote RCC progression. Mol Cell. 2025;85(14):2733-2748.e7.
2. Tang YG#, Dai CY#, Yang HH#, Yang X#, Chen ZY, Dou JX, Zhang LX, Bai T*, Zheng JF*. KAT8-mediated MDH2 lactylation promotes renal cancer progression by enhancing mitochondrial function and stress resistance. Int J Biol Macromol. 2025;322(Pt 1):146571.
3. Zhang LX#, Zhang HN#, Tang YG#, Dai CY, Zheng JF*. SRSF3 suppresses RCC tumorigenesis and progression via regulating SP4 alternative splicing. Biochim Biophys Acta Mol Cell Res. 2024:1871(8):119841.
4. Dai CY#, Cao JF#, Tang YG, Jiang YX, Luo CH*, Zheng JF*. YTHDF3 phase separation regulates ccRCC development via HSPA13-dependent immune evasion. Cancer Sci. 2024;115(8):2588-2601.
5. Ma YZ#, Fang ZY#, Zhang HN#, Qi YJ, Mao YK, Zheng JF*. PDZK1 suppresses TNBC development and sensitizes TNBC cells to erlotinib via the EGFR pathway. Cell Death Dis. 2024;15(3):199.
6. Qi YJ#, Ma YZ#, Peng ZQ, Wang L, Li LX, Tang YL, He JQ, Zheng JF*. Long noncoding RNA PENG upregulates PDZK1 expression by sponging miR-15b to suppress clear cell renal cell carcinoma cell proliferation. Oncogene. 2020;39(22):4404-4420.
7. Ma YZ#, Qi YJ#, Wang L, Zheng ZX, Zhang Y, Zheng JF*. SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis. Free Radic Biol Med. 2019;134:458-467.