
Prof. Yongbin Chen
Kunming Institute of Zoology, Chinese Academy of Sciences, China
Title: The beauty of interdisciplinary study between evolutionary biology and tumor biology
Abstract:
Biography:
Dr. Chen obtained
his Ph.D. in Shanghai Institute of Biochemistry and Cell
Biology, CAS,China(2005), and
did post-doctoral study with
Dr. Jin Jiang in UT southwestern medical center atDallas,USA. He was recruited
as a Principle Investigator in Kunming Institute of Zoology, CAS,China, by Thousand
Youth Talents Plan in 2012. Dr. Chen’s research focuses on
identifying novel biomarkers involved in tumorigenesis and
deciphering the underlying functional molecular mechanisms. Hypoxia occurs naturally at high-altitudes as well as many pathological
conditions (e.g. tumor). His lab uses large-scale comparative population
genomic data to reveal the genetic mechanism and species specific features
underlying high-altitude adaptation of Tibetan mammals, and has uncovered
multiple novel positively selected genes dysregulated in multiple types of
solid tumors, which provides new strategy identifying novel biomarkers for
cancers.