Dr. Faisal Ali
Sana'a University, Yemen
Title: Nutritional Status and Metabolic Profile Among Yemeni Patients with Type 2 Diabetes Mellitus
Abstract:
Background: Type 2 diabetes
mellitus (T2DM) is a major metabolic disorder frequently accompanied by
nutritional imbalances, poor glycemic control, and abnormalities in lipid
metabolism. Comprehensive nutritional and metabolic assessment is essential for
identifying modifiable risk factors and improving diabetes management,
particularly in resource-limited settings.
Aim: To assess
nutritional status and metabolic profiles among patients with T2DM and explore
the relationships between glycemic indices, anthropometric measurements, and
lipid parameters.
Methods: A laboratory-based
cross-sectional study was conducted among 145 patients with confirmed T2DM
attending routine follow-up and health assessments at the National Center of
Public Health Laboratories in Sana’a, Yemen, between January and July 2022.
Demographic characteristics, nutritional status, and relevant clinical and
lifestyle information were assessed. Anthropometric measurements included body
mass index (BMI), while metabolic assessment included fasting blood glucose
(FBG), glycated hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TG),
low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein
cholesterol (HDL-C). Statistical analyses included descriptive statistics and
correlation analysis to examine associations among the study variables.
Results: The mean age of
participants was 54.35 ± 8.02 years, and 60.7% were male. The mean BMI was
25.02 ± 5.22 kg/m². Regarding nutritional status, 35.9% of participants were
classified as underweight, 6.9% as having normal weight, 25.5% as overweight,
and 31.7% as obese. Poor glycemic control was observed in 66.9% of participants,
compared with 33.1% with good glycemic control. Assessment of lipid parameters
indicated that 57.2%, 71.7%, 66.9%, and 97.2% of participants were classified
as having controlled TC, TG, HDL-C, and LDL-C levels, respectively, according
to the study's classification criteria. Correlation analysis demonstrated
positive associations of glycemic indices with BMI, TC, TG, and LDL-C, whereas
negative associations were observed with HDL-C.
Conclusion: These
findings emphasize the importance of integrating nutritional assessment,
glycemic monitoring, and lipid profile evaluation into routine diabetes care to
facilitate early identification and management of metabolic abnormalities,
particularly in resource-limited settings.
Keywords: Type 2
diabetes mellitus; Nutritional status; Metabolic profile; Glycemic control;
Glycated hemoglobin; Lipid profile; Dyslipidemia.
Biography:
Dr. Faisal Ali, is an accomplished academic, physician, and biomedical researcher specializing in metabolic health, clinical nutrition, obesity, diabetes mellitus, and cardiometabolic disorders. He is an Associate Professor at the Faculty of Medicine and Health Sciences, Sana’a University, Yemen, where he contributes to medical and health sciences education, clinical research, postgraduate training, and the advancement of evidence-based healthcare. He currently serves as Vice-Dean for Academic Affairs and Graduate Studies at the Faculty of Applied Medical Sciences, Sana’a University, and has been an Adjunct Research Advisor at the Nan Yang Academy of Sciences (NAS), Singapore, since 2018. His international academic experience also includes postdoctoral research training at Universiti Putra Malaysia. His research interests span clinical and translational research, with a particular focus on metabolic health, obesity, diabetes, nutrition-related metabolic disorders. With a strong record of international scientific publications and interdisciplinary research collaborations, he has made significant scholarly contributions to understanding both the pathophysiological and molecular mechanisms, clinical implications, and management of metabolic and chronic diseases. He has received numerous national and international awards in recognition of his academic and research achievements. He has also supervised and mentored many postgraduate students at both the Master’s and PhD levels, including students from national and international academic settings, contributing to the development of emerging researchers and the advancement of postgraduate research capacity.